SARS-CoV-2 antibody after COVID-19 vaccination in patients with multiple sclerosis

type of intervention

Prospective cohort study

recruitment status

Recruiting

region

NSW, QLD, VIC, WA

type of ms

Primary progressive MS, Relapsing MS, Relapsing remitting MS, Secondary progressive MS

Brief summary

COVID-19 vaccines are now being rolled out. Many people living with MS are treated with drugs that affect their immune system, and there is not a lot of specific data relating to the administration of the COVID-19 vaccines to a person with MS who is treated for their disease. This is a multi-center study to determine the COVID-19 vaccine immunogenicity and to assess the protection given by vaccines in people living with MS.

Inclusion criteria

– Diagnosed Multiple Sclerosis according to 2017 McDonald criteria
– Treatment by any TGA-approved Disease Modifying Therapy (DMT) for MS, e.g. ocrelizumab, alemtuzumab, natalizumab, fingolimod, cladribine, beta-interferon, copaxone, dimethylfumarate, ofatumumab, siponimod, glatiramer acetate.
– Recipient of COVID-19 vaccine (Pfizer, Astra Zeneca, or Novavax).
– Is able to give consent

Exclusion criteria

Non-English speaking

Anticipated start date

May 2021

Recruitment contacts

Fabienne Brilot-Turville, fabienne.brilot@sydney.edu.au

Region

NSW/VIC/QLD/WA

Ethics approval

Yes

Last updated

21/06/2021

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