PLATYPUS – the Australian extension of the OCTOPUS trial
PLATYPUS is the Australian extension of a revolutionary trial based in the United Kingdom (UK) called OCTOPUS, which aims to enroll participants in the UK and Australia over the next few years. OCTOPUS (including PLATYPUS) is a trial which will test multiple treatments with the aim to find one that can slow down, and ultimately […]
Fatigue In Relapsing Multiple Sclerosis – Epstein Barr Virus (FIRMS-EBV) Treatment Trial
Fatigue is a common symptom for many people with MS and it does not respond to traditional MS treatments. It has been suggested that fatigue in MS could relate to chronic infection with the Epstein Barr Virus (EBV). In this clinical trial, two drug therapies with antiviral effects against EBV will be tested for their […]
Phase III, multicentre, randomised, double-blinded, placebo-controlled, MAMS trial of SpironolacTone and famciclOvir in the treatment of Progressive MS to prevent disability progression (STOP-MS)
Multiple sclerosis (MS) is a potentially devastating disease of the central nervous system and progressive MS, which occurs in up to two-thirds is the most severe form. Current therapies for MS have limited effect in the progressive stage. Recent studies have confirmed that the primary cause of MS is latent infection with Epstein-Barr virus (EBV). […]
The Real Price of Health: Experiences of Out-of-Pocket Costs in Australia.
Researchers from the College of Health and Medicine at the Australian National University are conducting a survey to examine the impact of out-of-pocket health costs on people with chronic conditions and carers. Understanding the impact of these on the day-to-day lives of people living with chronic conditions will provide important new knowledge, and an opportunity […]
Tailoring nutrition research to the multiple sclerosis (MS) community.
We are inviting adults with multiple sclerosis (MS) living in Australia to participate in an online survey to capture their opinions about the future directions of nutrition research for people with multiple sclerosis. The survey has been designed to include questions that will allow us to gain a better understanding of the needs of the […]
Developing ‘Nutrition and MS’ educational tool for healthcare professionals: Gathering healthcare professionals and people living with MS perspectives through separate co-design workshops
What is a co-design workshop? A collaborative session where your insights and ideas will help us design an educational tool on nutrition and MS for healthcare professionals. This is going to be a separate workshop for healthcare professionals and people living with MS. Why participate? Your experience and insights are invaluable. Together, we […]
Motherhood choice in multiple sclerosis (MoMS)
The study aims to pilot two developed questionnaires about MS and pregnancy/motherhood in different countries and to explore the needs of women with MS who considering pregnancy. One of the questionnaires, the motherhood/pregnancy choice and worries questionnaire (MPWQ), is designed to measure concerns, attitudes and coping strategies regarding pregnancy and motherhood. [1, 2] The second […]
Determining factors influencing implementation decisions in healthcare
This study aims to ascertain relevant considerations and contextual factors that influence stakeholders’ decisions to implement innovations. An innovation may be a new intervention, strategy, model of care, or therapy. This study has a particular focus on economic factors but will also explore non-economic factors influencing implementation. We will use a discrete choice experiment methodology […]
A randomized, double-blind, Phase 3 study comparing efficacy and safety of SAR441344 to placebo in adult participants with non-relapsing secondary progressive multiple sclerosis (FREVIVA)
This is a Phase 3 clinical trial. Its aim is to demonstrate the efficacy and safety of an investigational drug compared to placebo in participants with Secondary Progressive MS. Globally, approximately 900 participants will be randomly assigned to the investigational drug or placebo. This is a double-blind study. This means the study doctor and participant […]
Measuring mobility that matters to persons with multiple sclerosis: A co-design consumer engagement and Photovoice approach.
Through co-design and participatory action research we aim to establish which aspects of walking impact the participation in life activities of persons with multiple sclerosis and co-design walking outcomes that reflect the priorities of persons with multiple sclerosis. You will be asked to take photos of contexts where your walking impairment has impacted your ability […]