This project will evaluate the effects of a non-invasive technique known as paired corticospinal-motoneuronal stimulation (PCMS), which uses precisely timed magnetic brain stimulations (from transcranial magnetic stimulation, TMS) and peripheral nerve stimulations. PCMS aims to strengthen brain and spinal cord connection strength, and may result in stronger, more efficient muscle activation, even in motor pathways weakened by MS. We will be the first to systematically assess the effects of PCMS in MS. This study will generate foundational data for future clinical trials.

• Confirmed diagnosis of MS
• Aged 18–25 years

• Relapse within the last 3 months
• Other significant neurological/psychiatric/musculoskeletal conditions
• Implanted medical devices or metal objects in the body
• History of seizures
• Currently pregnant

Currently recruiting

If you have any questions or would like more information, please email the following researchers:

Jano van der Merwe, Email: jvanderm@bond.edu.au

Dr Jacob Thorstensen, Email: jthorste@bond.edu.au, Phone: +61 7 5595 4457

For further details about the study and procedures, please reach out to a member of the study team who will provide you with an information sheet.

This study is being undertaken at a single site, Bond University:  14 University Dr, Robina QLD 4226.

QLD

Yes

16/06/2026