Medical Procedure
Recruiting
VIC
Relapsing remitting MS
This trial is testing whether an autologous (self) haematopoietic stem cell transplant (AHSCT) for highly active, treatment resistant multiple sclerosis reduces MS disease activity over 5 years.
The treatment involves: treatment, collection and freezing of stem cells from the patient’s blood; chemotherapy (BEAM-ATG) to destroy the immune system; reinfusion of the patient’s own stem cells.
For full details of the treatment protocol please visit Australian New Zealand Clinical Trials Registry website.
General eligibility criteria must be met for all patients entering the trial and referral from a neurologist is required. This includes general health criteria relating to cardiovascular, lung and liver health, absence of serious infectious diseases, negative pregnancy test for women, age between 18 and 55 years and ability to provide informed consent.
Specific eligibility criteria for multiple sclerosis must also be met. These are as follows:
This study defines ‘highly active’ relapsing remitting MS as:
and
or
For more background information about AHSCT for MS please visit the MS Research Australia website www.msra.org.au/AHSCT.
For full details of inclusion and exclusion criteria please visit Australian New Zealand Clinical Trials Registry website.
Started
Prof Richard MacDonell
Austin Health, 145 Studley Road,
Heidelberg Vic 3084, Australia
Email: richard.macdonell@austin.org.au
Phone: 03 9496 3705
Fax: 03 9496 2153
Full details of the trial can be found on the ANZCTR clinical trials database.
VIC
29/06/2023
ACTRN12616000151437
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