Clinical Trials

Why do people with multiple sclerosis fatigue more easily than healthy individuals?

Type of Study/Intervention


Recruitment Status


Form of MS

All forms of MS (Relapsing remitting MS, Secondary progressive MS, Primary progressive MS, Relapsing MS) and people without MS

Brief Summary

Do you fatigue easily during exercise? Up to 80% of people with MS experience fatigue, and half of those affected by fatigue report challenges when performing work, exercise, and activities of daily living.

Researchers at Griffith University are examining why people with MS fatigue more during exercise than people without MS. We are investigating both the characteristics of the muscle, and the function of neural pathways in people with MS during a series of fatiguing biceps contractions over two visits to our Neural Control of Movement Laboratory. We are hoping that these findings will better understand the fatigue characteristics in this population and allow us to improve treatments of MS that help manage and alleviate symptoms of fatigue.

Participants will be offered a $100 Coles/Woolworths gift card for their involvement.

Inclusion Criteria

• People with and without MS
• Age 20-65 years old
• Male and Female
• Able to perform an upper body (biceps) muscle contraction

Exclusion Criteria

• Pregnancy
• Visual impairment
• Neurological disorders (besides MS)
• Implanted medical devices (pacemaker etc.) or metal within the body
• Peripheral nerve pathologies affected the upper limb
• Experienced a MS relapse within the last 3 months

Anticipated Start Date

Already commenced August 2020

Recruitment Contact

Emily Brotherton
Phone: 0474 507 600

Further Details

Please contact Emily Brotherton for further details


Southport, Gold Coast, QLD

Ethics Approval


Last updated


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