Clinical Trials

Primary Progressive MS Study

Type of Study/Intervention


Recruitment Status


Form of MS

Primary progressive MS

Brief summary

Primary Progressive MS (PPMS) is a type of Multiple Sclerosis that affects 1 in 10 people with the disease, and for which current MS treatments are not effective. Little specific research has been done in PPMS and our understanding of the risk factors for this variant of MS is poor.

This study is a case-control study where the cases will be followed longer term.

The case-control study aims to examine whether the established risk factors for MS also hold in people with PPMS and whether we can identify novel risk factors for this group. The longitudinal component examines which factors are associated with disease progression in people with PPMS.

This project will improve the understanding of the aetiology of MS for PPMS, which will contribute to unravelling the mechanisms of PPMS and ultimately the development of treatments and interventions.

Inclusion criteria

Australian residents with PPMS, over the age of 18 years

Exclusion criteria

Further details can be found on the website

Anticipated Start Date

The study has already started

Recruitment contacts

Alice Saul
Phone: 03 6226 4269

Further details

Full details of the trial can be found on the study website



Last Updated

19 Nov 2020

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