Clinical Trials

Finding the right balance with participation in exercise and sport for individuals with multiple sclerosis

Type of Study/Intervention


Recruitment Status


Form of MS

Relapsing remitting MS

Brief summary

The objective of this study is to assess the feasibility of a Flexible Exercise Participation Program (FEPP) for people with minimal disability from multiple sclerosis. The 12-week FEPP will guide participants to independently participate in their preferred sport or exercise at a location of their choice. Exercise progression will be guided by individual energy levels and a weekly telephone coaching session with a physiotherapist. Participation in exercise or sport will be recorded in parallel with assessment of disease biomarkers, subjective vitality and high-level mobility. The aim of the study is to help increase participation in sport or exercise for people with multiple sclerosis.

Inclusion criteria

(i) diagnosis of relapsing remitting MS as defined by the 2017 McDonald criteria; (ii) independent mobility as defined by Expanded Disability Status Scale (EDSS) level 0-3.5 33; (iii) stable i.e. not worsening in past three months on disease modifying drugs (e.g. alemtuzamab, natalizumab and ocrelizumab); (iv) aged 18 years or over; (v) able to provide informed consent.

Exclusion criteria

(i) any concomitant neurological condition or (ii) an additional health condition that would prohibit their participation in aerobic exercise or sport.

Anticipated start date


Recruitment contacts

Ms Moira Smith
James Cook University
P: 07 47816003



Further details

Further details can be viewed on the ANZCTR website: ACTRN12620000076976

Ethics approval


Last updated

19 Nov 2020

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