Clinical Trials

A Pilot Study of Cognitive Behavioural Therapy for Migraine in Multiple Sclerosis

Type of Study/Intervention


Recruitment Status


Form of MS

Relapsing remitting MS

Brief summary

Individuals with MS and migraine can face difficulties with thinking skills (e.g. concentration and memory), mood, fatigue, work and social activities. However, to date, there has been no CBT program developed that is specifically tailored to these difficulties for individuals with MS and migraine. The project aims to assess how feasible and acceptable such a CBT program would be among people with MS and migraine.

The brief cognitive behavioural therapy program will be conducted in five sessions across, with one-hour weekly sessions and a follow-up phone call 4-weeks later. The study will be conducted entirely on telehealth via internet, so participants can attend from home. Sessions will be on a one-on-one basis, with a neuropsychology registrar. Therapy will be provided free of charge.

The CBT program itself targets reducing the frequency and intensity of migraines, and in turn improve fatigue, low mood, anxiety, thinking skills, and work and social functioning. The techniques learnt in therapy aim to prevent migraines from occurring and when they do occur, lessen their impact on daily life. This CBT includes education about migraines, relaxation strategies, skills to adapt negative thoughts, and strategies to manage thinking skills difficulties (e.g. with concentration).

Inclusion criteria

1. Diagnosis of migraine
2. Diagnosis of relapsing-remitting multiple sclerosis
3. English fluency
4. Medicare eligibility
5. Internet access

Exclusion criteria

1. Currently receiving psychological therapy or seeing a psychologist
2. Other diagnosed neurological disease (e.g., traumatic brain injury, stroke, epilepsy)
3. Severe psychiatric symptoms (e.g., psychosis, severe depression)

Anticipated start date


Recruitment contacts

Ms Pavika Thevar
Phone: +61 0433 151 949

Further details

Further details can be found here.



Ethics approval


Last updated


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